منابع مشابه
Dmd052548 1686..1694
Despite metronidazole’s widespread clinical use since the 1960s, the specific enzymes involved in its biotransformation have not been previously identified. Hence, in vitro studies were conducted to identify and characterize the cytochrome P450 enzymes involved in the formation of the major metabolite, 2-hydroxymetronidazole. Formation of 2-hydroxymetronidazole in human liver microsomes was con...
متن کاملDev105940 1694..1704
The oocyte (maternal) nucleolus is essential for early embryonic development and embryos originating from enucleolated oocytes arrest at the 2-cell stage. The reason for this is unclear. Surprisingly, RNA polymerase I activity in nucleolus-less mouse embryos, as manifested by pre-rRNA synthesis, and pre-rRNA processing are not affected, indicating an unusual role of the nucleolus. We report her...
متن کاملMarcello Malpighi (1646-1694)
Malpighi was born in 1628 in Crevalcore, Bologna, Italy, and he was baptized 10 March of that year. His parents were Maria Cremonini and Marcantonio Malpighi. He entered the University of Bologna [5] in Bologna in 1646, and his tutor Francesco Natali encouraged him to study medicine, which he began in 1649. While in medical school he was one of only a few students permitted to attend vivisectio...
متن کاملDev118216 1684..1694
E-cadherin (E-cad) is the main component of epithelial junctions in multicellular organisms, where it is essential for cell-cell adhesion. The localisation of E-cad is often strongly polarised in the apicobasal axis. However, the mechanisms required for its polarised distribution are still largely unknown. We performed a systematic RNAi screen in vivo to identify genes required for the strict E...
متن کاملThe Expedition towards Venus
A project of an expedition towards planet Venus, which is carried out in two stages, is considered. At the first stage, a space train, consisting of a locomotive and a tank with working substance, delivers onto Venus orbit the landing capsule with the Venus plane and the Venus rover, as well as the tank-container with liquid hydrogen, which is used subsequently for return of the expedition onto...
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ژورنال
عنوان ژورنال: The English Historical Review
سال: 1894
ISSN: 0013-8266,1477-4534
DOI: 10.1093/ehr/ix.xxxiii.130